PROGECOT-200 SOFTGEL CAP

Progecot-200 Softgel Capsules 

Brand: Progecot-200
Dosage form: Soft gelatin capsule
Strength: 200 mg
Pack shown: 10 × 1 × 10 softgel capsules
Routes stated on the pack: Oral / Vaginal / Rectal

1. Composition

Each soft gelatin capsule contains:

IngredientQuantityPurposeNatural Micronised Progesterone200 mgActive pharmaceutical ingredient (API)Suitable pharmaceutical vehicleq.s.Solubilization/suspension and delivery of progesteroneSoft gelatin shellq.s.Encapsulation of the fill materialOther approved excipientsq.s.Stability, manufacturing and physical properties

The photograph confirms Natural Micronised Progesterone 200 mg, but it does not provide a sufficiently clear complete list of inactive ingredients or their quantities. Therefore, exact excipients should not be presented as confirmed from the image alone.

2. Active Pharmaceutical Ingredient — Natural Micronised Progesterone

Progesterone: 200 mg per capsule

Progesterone is a naturally occurring steroid hormone belonging to the progestogen group. It is chemically identical to the progesterone produced naturally by the human body.

Why “micronised”?

Micronisation means that the progesterone particles have been reduced to a very small particle size.

This provides:

• Increased surface area

• Improved dissolution

• Better dispersion in the formulation

• Improved absorption compared with larger progesterone particles

Micronised progesterone is commonly incorporated into softgel formulations because progesterone has very low aqueous solubility.

3. Softgel fill formulation

The progesterone is incorporated into a suitable lipid/oily pharmaceutical vehicle.

The vehicle can help:

• Disperse or solubilize micronised progesterone

• Improve consistency of the dose

• Facilitate absorption

• Maintain physical stability of the fill

• Allow the formulation to be enclosed in a soft gelatin shell

Possible pharmaceutical vehicles used in progesterone softgel formulations can include vegetable oils or other lipid-based vehicles.

However, the specific vehicle used in Progecot-200 cannot be confirmed from the photograph. For example, it would be inappropriate to state that a particular oil is present unless it appears in the manufacturer's approved composition.

4. Soft gelatin shell

The capsule shown is a soft gelatin capsule.

A conventional softgel shell generally contains three major components:

A. Gelatin

Gelatin forms the structural matrix of the capsule shell.

It provides:

• Mechanical strength

• Flexibility

• Shape retention

• Protection of the fill

B. Plasticizer

A plasticizer provides flexibility to the gelatin shell and helps prevent brittleness.

Examples used in softgel manufacturing can include:

• Glycerol

• Sorbitol/sorbitol solutions

The actual plasticizer used in Progecot-200 should be verified from the manufacturer's specification.

C. Purified water

Water is used during gelatin-shell manufacture to hydrate and process the gelatin.

Additional materials such as colouring or opacifying agents may be used depending on the approved shell formulation.

5. Excipients

For a pharmaceutical softgel, excipients can be divided according to their function:

Fill excipients

These form the medium in which progesterone is dispersed or dissolved.

Antioxidants/stabilizers

May be incorporated into lipid-based formulations when necessary to improve stability.

Shell excipients

These provide the required flexibility, appearance and physical properties of the softgel shell.

Colouring/opacifying agents

May be used to provide the characteristic appearance or protect light-sensitive contents.

None of these should be treated as confirmed ingredients of Progecot-200 unless they are listed in the manufacturer's approved documentation.

6. Strength calculation

Each capsule contains:

Progesterone = 200 mg

Therefore:

• 1 capsule: 200 mg progesterone

• 10 capsules: 2,000 mg = 2 g

• 1 strip of 10: 2 g progesterone

• 10 strips × 10 capsules: 100 capsules × 200 mg = 20,000 mg = 20 g

These figures represent the active progesterone only, not the total weight of the softgel capsule.

7. Pharmaceutical classificationParameterDetailsBrand nameProgecot-200Active ingredientNatural Micronised ProgesteroneStrength200 mgDosage formSoft gelatin capsuleDrug classNatural progestogenAdministration shownOral / Vaginal / RectalPack10 × 1 × 10 softgel capsulesActive ingredient per capsule200 mg

8. Professional composition statement

For a PCD/product catalogue, you can write:

COMPOSITION:
Each soft gelatin capsule contains:
Natural Micronised Progesterone IP 200 mg
Excipients q.s.
Soft gelatin shell q.s.
Dosage form: Soft Gelatin Capsules.

Or, in a more detailed product-profile format:

Each soft gelatin capsule contains Natural Micronised Progesterone 200 mg in a suitable pharmaceutical vehicle and an appropriate soft gelatin shell containing pharmaceutical-grade excipients q.s.

Important

The exact quantitative formula—for example, the precise amount of progesterone vehicle, gelatin, glycerol/sorbitol, water, antioxidant, colour and other excipients—cannot be determined from the photograph. If you need the composition for a manufacturing formula, product dossier, PCD, WHO-GMP document, or regulatory submission, it should be taken from the manufacturer's approved Master Formula/finished-product specification rather than estimated.