MEFETT-D TAB

MEFETT-D Tablets 

Brand: MEFETT-D
Manufacturer: Accott Healthcare
Dosage form: Tablet
Pack shown: 10 × 10 tablets

The available product information for Accott's Mefett-D identifies it as the Drotaverine 80 mg + Mefenamic Acid 250 mg combination. (Tradeindia)

IngredientAmount per tabletMain functionDrotaverine Hydrochloride80 mgAntispasmodic; relaxes smooth muscle and reduces cramps/spasmsMefenamic Acid250 mgNSAID; reduces pain and inflammationExcipientsq.s.Tablet formation, stability and appearance

1. Drotaverine Hydrochloride — 80 mg

• A smooth-muscle antispasmodic.

• Relaxes spasmed smooth muscle, particularly in the gastrointestinal and genitourinary tracts.

• Helps relieve cramping and colicky/spasmodic pain.

• It works mainly by inhibiting phosphodiesterase-4 (PDE-4), increasing intracellular cyclic AMP and reducing smooth-muscle contraction.

2. Mefenamic Acid — 250 mg

• A non-steroidal anti-inflammatory drug (NSAID) of the fenamate group.

• Reduces prostaglandin production through inhibition of cyclooxygenase enzymes.

• Provides analgesic and anti-inflammatory effects.

• Commonly used for painful conditions including menstrual pain and other acute pain.

Why these two are combined

They work through different mechanisms:

Drotaverine → relaxes the muscle spasm/cramp
Mefenamic acid → reduces the pain and inflammation

Therefore, the combination can be prescribed for spasmodic abdominal pain, menstrual cramps (dysmenorrhea), biliary/urinary colic and other smooth-muscle spasm–associated pain, depending on the diagnosis. The Accott listing specifically identifies Mefett-D as Drotaverine 80 mg + Mefenamic acid 250 mg. (Tradeindia)

Important precautions

• Mefenamic acid can cause stomach irritation, ulcers and gastrointestinal bleeding, particularly with prolonged use.

• Avoid taking it together with other NSAIDs such as ibuprofen, diclofenac, naproxen or nimesulide unless specifically prescribed.

• Drotaverine may cause dizziness, nausea, headache or low blood pressure in some people.

• Extra caution is needed with a history of stomach ulcer/bleeding, kidney disease, NSAID allergy or significant heart disease.

• Taking the medicine with/after food may reduce stomach irritation from mefenamic acid.

Final composition

MEFETT-D = Drotaverine Hydrochloride 80 mg + Mefenamic Acid 250 mg per tablet + excipients q.s. (Tradeindia)

The exact Accott-specific excipient list cannot be confirmed from the front of the package shown.