TRYOT-PLUS TAB

TRYCOT-PLUS Tablets 

Trypsin, Bromelain, Rutoside Trihydrate & Diclofenac Sodium Tablets

Based on the standard formulation corresponding to this exact four-drug combination, the composition is Trypsin 48 mg + Bromelain 90 mg + Rutoside Trihydrate 100 mg + Diclofenac Sodium 50 mg per tablet. This strength is also documented for the same combination in Indian drug references and regulatory records. (MIMS)

Detailed composition — per tablet

IngredientAmountMain roleTrypsin BP48 mgProteolytic enzyme; used as part of anti-inflammatory/anti-oedema therapyBromelain90 mgProteolytic enzyme derived from pineapple; used to help reduce swelling and inflammationRutoside Trihydrate BP100 mgFlavonoid compound with antioxidant/capillary-stabilizing propertiesDiclofenac Sodium IP50 mgNSAID analgesic and anti-inflammatory medicineExcipientsq.s.Tablet formulation ingredients

A published product specification for this same formulation gives Trypsin BP 48 mg, Bromelain 90 mg, Rutoside Trihydrate BP 100 mg and Diclofenac Sodium IP 50 mg, with excipients added as required. (Zuventus)

What each ingredient does

1. Trypsin — 48 mg
Trypsin is a proteolytic enzyme. In this combination it is intended to contribute to reduction of inflammatory swelling and tissue oedema.

2. Bromelain — 90 mg
Bromelain is a mixture of proteolytic enzymes obtained from pineapple. It is used in combination products intended to reduce inflammatory swelling and discomfort.

3. Rutoside trihydrate — 100 mg
Rutoside (rutin derivative) is a flavonoid. It is included for its antioxidant and vascular/capillary-supporting effects and may contribute to reducing inflammatory oedema.

4. Diclofenac sodium — 50 mg
This is the principal conventional painkiller/NSAID in the combination. It inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin production and thereby reducing pain, inflammation and fever.

What the combination is used for

This type of combination is prescribed for pain accompanied by inflammation and swelling, for example:

• Muscle and soft-tissue injuries

• Sprains and strains

• Joint inflammation

• Post-operative swelling and pain

• Dental procedures/inflammation

• Certain musculoskeletal conditions

Similar formulations are specifically described for pain, inflammation and oedema associated with injuries and surgery. (Pharmed Limited)

Important caution

Because Diclofenac 50 mg is an NSAID, this is not simply a digestive or enzyme supplement. It can cause stomach irritation, ulcers or gastrointestinal bleeding and can affect kidney function and blood pressure in susceptible people.

Avoid combining it with other NSAIDs such as ibuprofen, naproxen, aceclofenac or additional diclofenac unless a doctor specifically advises it. Extra caution is needed with a history of stomach ulcers/bleeding, kidney disease, significant heart disease, or use of blood thinners.

In short:

TRYCOT-PLUS = Trypsin 48 mg + Bromelain 90 mg + Rutoside Trihydrate 100 mg + Diclofenac Sodium 50 mg per tablet. (MIMS)

If you want, I can also explain TRYCOT-PLUS + UDN-300 + XYLOCOT + HAIR-COT + Cranbee together — why a doctor might prescribe all of them, what each one is for, and whether there are important interactions between them.