RABITIME-ADVANCE CAP

Rabitime-Advance Capsules

Prescription medicine (Rx)

Rabitime-Advance is a combination medicine containing rabeprazole sodium and two formulations of domperidone. It is intended to reduce stomach acid and improve movement of food through the upper digestive tract. It may be prescribed for selected patients with acid reflux, gastroesophageal reflux disease (GERD), and associated symptoms such as nausea, bloating or delayed gastric emptying.

1. Composition

According to the packaging in your photograph, each capsule contains:

Ingredient

Strength

Form

Rabeprazole sodium

20 mg

Enteric-coated (EC)

Domperidone

10 mg

Immediate-release (IR)

Domperidone

20 mg

Sustained-release (SR)

Total domperidone per capsule

30 mg

This is an important consideration because domperidone can affect heart rhythm, particularly at higher doses or in susceptible patients.

2. How the ingredients work

Rabeprazole 20 mg (EC)

Rabeprazole is a proton pump inhibitor (PPI). It blocks the acid-producing pumps in the stomach lining, reducing acid secretion and allowing inflamed tissue in the esophagus to heal. The enteric coating protects the medicine from stomach acid until it reaches the intestine.

Domperidone 10 mg (IR) + 20 mg (SR)

Domperidone is a dopamine D2 receptor antagonist with anti-nausea and gastrointestinal prokinetic effects. The immediate-release portion is designed to release earlier, while the sustained-release portion releases more gradually. This does not eliminate the risks associated with the total 30 mg dose.

3. Uses and indications

A clinician may consider the ingredients in this combination for:

• Acid reflux and GERD, particularly when accompanied by nausea.

• Acid-related inflammation of the esophagus.

• Nausea and vomiting associated with certain gastrointestinal disorders.

• Selected cases of impaired gastric motility, after assessing the underlying cause.

However, these are not all established indications for this particular combination. European regulators restrict domperidone to short-term relief of nausea and vomiting because evidence for treating bloating and heartburn is insufficient to justify its cardiac risks.

European Medicines Agency (EMA)

4. Dosage and administration

Follow the prescribing doctor's instructions. The exact dosing schedule for this brand cannot be established from the photograph alone.

For medicines containing rabeprazole, administration before a meal is common. Swallow the capsule whole with water unless its official leaflet specifies otherwise. Do not crush or chew sustained-release pellets.

Important dosage precaution

One Rabitime-Advance capsule already contains 30 mg of domperidone. European guidance sets the maximum oral adult dose at 30 mg daily, normally for no longer than one week. Do not take additional domperidone or increase the frequency without medical review.

European Medicines Agency (EMA)

5. Side effects

Possible side effects of these ingredients include:

More common

Less common but important

Headache

Abnormal heart rhythm

Dry mouth

Allergic reactions

Abdominal discomfort

Severe or persistent diarrhea

Nausea

Electrolyte disturbances

Constipation or diarrhea

Hormonal effects, such as breast tenderness or discharge

These effects are associated with the ingredients; their frequency for this specific brand has not been verified.

Seek urgent medical attention if you develop fainting, a rapid or irregular heartbeat, severe dizziness, difficulty breathing or swelling of the face or throat.

6. Who should take extra precautions?

Domperidone requires particular caution in people over 60, those with heart disease or abnormal ECG findings, significant liver impairment, or abnormal potassium or magnesium levels. Some antibiotics, antifungals and heart-rhythm medicines can interact dangerously with it.

European Medicines Agency (EMA)

+1

Tell your doctor about all prescription medicines, supplements and medical conditions before taking this combination. Pregnancy and breastfeeding also require an individual medical assessment.

7. Packaging and price

Details visible in your photograph

Item

Information

Brand

Rabitime-Advance

Dosage form

Capsules

Pack

10 × 10 capsules

Strip

10 capsules

Printed MRP

₹210 per strip, inclusive of GST

Approximate price per capsule

₹21

Batch number

THC-26076

Manufacturing date

September 2026

Expiry date

August 2028

Logo on blister

Riso

The MRP is the printed price, not a verified current retail price. The photograph does not establish the medicine's authenticity or regulatory approval status.

8. Storage

Keep the capsules in their original blister packaging, protected from heat, moisture and direct sunlight. Follow the storage temperature specified on the carton, and keep them out of children's reach. Do not use them after the expiry date.

Key point: Rabitime-Advance combines acid suppression with a relatively high total amount of domperidone per capsule. It should be used only for an appropriate indication, with its dose, treatment duration and potential interactions checked by a healthcare professional.